Manuscript Writing Service
International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2017, Vol. 1, Issue 1, Part A

Spectrum of placental changes in Toxemia of pregnancy: A case series study
Author(s): Ananya Agrawal, Kaushal Kumar, Shashikant Kumar, Sunanda Nayak, Khushboo and Neelu Yadav
Abstract: 7Background: Toxemia of pregnancy is the leading cause of maternal mortality and is an important factor in fetal wastage. The incidence is high in developing countries with malnutrition, hypoproteinemia, and poor obstetric facilities.
Objectives: The present study was undertaken to analyze placental changes in the preeclampsia-eclampsia syndrome with a view to assess the significance of villous abnormalities by histopathological methods because these changes serve as a guide to the duration and severity of disease. Gross abnormalities noted were the placental infarcts, retroplacental hematoma, and calcification.
Results: The striking villous abnormalities observed in the study group were cytotrophoblastic proliferation (80%), thickening of the villous basement membranes (70%), increase in syncytial knots (82.5%), villous stromal fibrosis (72.5%), fibrinoid necrosis (77.5%), endarteritis obliterans (15%), decreased villous vascularity, and paucity of vasculosyncytial membranes (2.5%).
Conclusions: The gross abnormalities and villous lesions in the preeclampsia (P<0.001) and eclampsia syndrome (P<0.05) were significant.
Pages: 08-13 | 1154 Views | 522 Downloads
Download Full Article: Click Here
How to cite this article:
Ananya Agrawal, Kaushal Kumar, Shashikant Kumar, Sunanda Nayak, Khushboo and Neelu Yadav. Spectrum of placental changes in Toxemia of pregnancy: A case series study. International Journal of Clinical Obstetrics and Gynaecology. 2017; 1(1): 08-13.
International Journal of Clinical Obstetrics and Gynaecology