Abstract: Background: A simple test for glycemic status and its correlation with clinical features of insulin resistance will be more cost effective in diagnosing and treating with insulin sensitizers for the metabolic syndrome in Polycystic ovarian syndrome (PCOS). Current study aimed to to study the association of insulin resistance in women with PCOS.
Method: In this cross sectional study, 50 PCOS patients who attended our outpatient department according to Rotterdams criteria and we determined the insulin resistance among them.
Result: In our study 42% of the cases were between 25-29 years of age. 72% of them were married. 46 % had BMI of 18-24 and another 46% had BMI of 25-30. 36% of our study population had positive family history of PCOS and only 6% had family history of both PCOS and Diabetes. 17% of the patients had oligomenorrhoea. 18 patients (36%) had positive insulin resistance in this study out of which 9 patients also had impaired glycemic status. This was found to be statistically significant with p value of <0.001. Out of 12 cases of clinically evident hirsutism 9 patients (75%) had positive insulin resistance giving a significant p value of 0.001. Also 18 cases with acanthosis had insulin resistance with p value <0.001.
Conclusion: Therefore all cases of PCOS with impaired glycemic status had insulin resistance and so by evaluating the glycemic status and other clinical parameters like hirsutism, acanthosis, abdominal obesity and menstrual irregularities were able to arrive at the diagnosis of insulin resistance among study population.
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