Role of vitamin D in preeclampsia: Our experience
J Arumaikannu, S Usha Rani and S Shanthi
To assess the vitamin D status in preeclamptic and normal healthy pregnant women and to find out its association with preeclampsia.
Materials and Methods: Prospective case control study included 50 women with preeclampsia and 50 normotensive pregnant women. Serum vitamin D estimation was done. Correlation between vitamin D deficiency and preeclampsia was analysed statistically.
Results: Prevalence of vitamin D deficiency was comparable in both groups. Mean vitamin D level was statistically low in preeclampsia group. Severity of vitamin D deficiency did not correlate with the severity of preeclampsia. Age, parity and BMI were similar in both the groups. Gestational age and birth weight were statistically low in preeclampsia group. Cesarean section was significantly high in preeclampsia women.
Conclusion: Vitamin D deficiency is significantly associated with preeclampsia. Further studies are needed to document the role of vitamin D supplementation in prevention of preeclampsia.