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International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2019, Vol. 3, Issue 4, Part C

to study the diagnostic role of various risks of malignancy indices (RMI 1, 2, 3, 4) in the pre-operative evaluation of adnexal masses and to compare the four Rmi with each other in terms of various statistical parameters
Author(s): Dr. Tanya Agrawal and Dr. Ishita Ganguly
Abstract: Background: The present study Women presenting with acute or chronic abdominal pain along with an adnexal mass in routine as well as emergency hours. 200 females meeting the inclusion criteria during the study period, 100 in premenopausal and 100 in postmenopausal group after informed consent. Result: RMI 1 has the highest sensitivity, specificity and accuracy amongst overall population in the present study. Individual parameters including CA125 and Ultrasound findings have poor specificity and sensitivity respectively, thereby decreasing their accuracy as an individual screening tool in overall population. In premenopausal females, the values of all the statistical parameters of these screening tools decreases as these are mainly based on serum CA125 levels, which is a marker of epithelial ovarian malignancies. In postmenopausal females, the accuracy of all these screening tools increases due to high prevalence of epithelial ovarian cancers in postmenopausal females. RMI 1 has the highest sensitivity, while RMI 4 shares the highest specificity due to its high cut off value of 450. Overall, RMI 1 and RMI 3 have similar accuracy as a screening tool. Conclusion: The present study also concludes that RMI scoring system has better accuracy in comparison to the individual parameters like post-menopausal status, CA125 or ultrasound score as a screening tool in cases of suspicious ovarian malignancies. RMI 1 turned up as the most accurate tool for screening purposes with a sensitivity, specificity and accuracy of 89.93%, 86.11% and 85.5% respectively when compared to the gold standard of diagnosis. Considering the high fatality to case ratio of ovarian malignancies, RMI provides us with an opportunity of detecting ovarian malignancy at an earlier stage and thereby improving the prognosis and overall survival of patients.
Pages: 137-139 | 670 Views | 98 Downloads
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How to cite this article:
Dr. Tanya Agrawal and Dr. Ishita Ganguly. to study the diagnostic role of various risks of malignancy indices (RMI 1, 2, 3, 4) in the pre-operative evaluation of adnexal masses and to compare the four Rmi with each other in terms of various statistical parameters. International Journal of Clinical Obstetrics and Gynaecology. 2019; 3(4): 137-139. DOI: 10.33545/gynae.2019.v3.i4c.302
International Journal of Clinical Obstetrics and Gynaecology