Abstract: Background: Delaying this definitive management for severe preeclampsia to at least gain benefit of antenatal steroids and to organize resources for managing the anticipated complications is referred to as expectant management. Therefore, the present study was made attempt to study the maternal and perinatal outcome in severe preeclampsia.
Methods: The study was conducted in the Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal. One hundred and forty patients who had blood pressure ≥ 160/110 mm of hg with proteinuria of any degree or Blood pressure ≥ 140/90 mm of hg with proteinuria of ≥ 2+ were included in the study. Statistical analysis was done by applying chi-square.
Results: Mean arterial pressure of >127mm of Hg was found in 31.8% women with eclampsia and 18.2% with other complications. Hemoglobin > 13g% and total count > 11000 cells/cumm had no correlation with the maternal outcome related to severe preeclampsia. Platelets <1 lakh/ml were found to have correlation with other complications related to preeclampsia but not with eclampsia. Serum uric acid >7U/l was found to have significant correlation with eclampsia as well as other complications related to preeclampsia. Serum creatinine>1.2mg/dl 35.2% had eclampsia and 52.9% had other complications.
Conclusion: Mean arterial pressure, uric acid, platelet count, serum creatinine were found correlate significantly with poor maternal outcome in women with severe preeclampsia. Prematurity and fetal growth restrictions are the main factors causing perinatal morbidity/ mortality. Timely cesarean delivery seems to improve perinatal outcome in settings with facilities for newborn care.
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