International Journal of Clinical Obstetrics and Gynaecology
2019, Vol. 3, Issue 5, Part C
Successful outcome of pregnancy with protein c deficiency with bad obstetric history: A rare case report
Author(s): Yadav Sumitra and Goyal Anshita
Abstract: Protein C is thought to play a key role in the regulation of hemostasis, and its deficiency has been associated with an increased risk of thromboembolism. Protein C-deficient women are at particular risk of developing thromboembolic complications during pregnancy and delivery. The incidence of thromboembolic events is estimated to be 500-1000 times higher than in normal women. We report the case of a 28-year-old woman with previous deep vein thrombosis, PPH, BOH who experienced a successful pregnancy and delivery despite severe congenital protein C deficiency. She was ant coagulated with LMWH (enoxaparin) during the second part of her pregnancy. Our observation suggests that ambulatory full-dose subcutaneous low molecular weight heparin therapy during pregnancy constitutes adequate prevention. However, definite guidelines will require more extensive studies.
Yadav Sumitra, Goyal Anshita. Successful outcome of pregnancy with protein c deficiency with bad obstetric history: A rare case report. Int J Clin Obstet Gynaecol 2019;3(5):148-149. DOI: 10.33545/gynae.2019.v3.i5c.343
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