Abstract: Background: The third stage of labour commences with the complete delivery of the foetus and ends with the complete delivery of the placenta and its attached membranes. The present study was conducted to evaluate the scope of using carboprost in comparison with intramuscular oxytocin and providing single drug for third stage of labour which is effective as well as safe and associated with less side effects.
Materials & Methods: The present study was conducted on 220 females. Patients were randomly assigned into two equal groups. Third stage of labour was observed for sign of placental separation such as uterine tone, symphysis fundal height, lengthening of cord and gush of blood.
Results: Group 1 women received (10 Unit) oxytocin and group II women received (125 micrograms) carboprost. Each group had 110 patients. The mean maternal age in oxytocin group was 26.23+4.16 years and in carboprost group was 25.51+3.98 years. The mean duration of third stage of labour was 8.77+3.9 mins in oxytocin group and 7.59+3.9 mins in carboprost group. The difference was found to be statistically significant. In group I, mean blood loss was 264.69 ml and in group II was 175.15 ml.
Conclusion: Carboprost is better and cost effective alternative to intramuscular 10 units oxytocin in the prophylactic management of third stage of labor. Carboprost reduces the duration of third stage, amount of blood loss, decreases the requirements of additional oxytocin.
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