International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2020, Vol. 4, Issue 2, Part F

Correlation of vitamin D and Parathyroid hormone with insulin resistance in PCOS women
Author(s): Saumya Prasad, Pratima Mittal, Rekha Bharti and Jyotsna Suri
Abstract: Objectives: To investigate the relation of 25, hydroxyvitamin D concentration and parathyroid hormone with insulin resistance in PCOS women.
Methods: A cross-sectional study was conducted on 50 PCOS (Rotterdam’s criteria) women. Concentrations of 25, hydroxyvitamin D and PTH were measured along with serum levels of fasting sugar and insulin. The homeostasis model assessment index was used as the insulin resistance index.
Results: Total prevalence of vitamin D deficiency (<20ng/ml) was found to be 84% while increased parathyroid hormone level was observed in 64%. There was significant negative correlation between vitamin D deficiency and HOMA-IR (r=-0.67, p<0.01). Positive association was found between increased PTH levels (normal levels: 13.9- 38.3pg/ml) and HOMA-IR.
Conclusion: Vitamin D deficiency and high parathyroid levels are associated with glucose intolerance in PCOS women. Strong correlation between vitamin D deficiency and insulin resistance in PCOS women may suggest that normalization of vitamin D levels may correct insulin resistance.
Pages: 348-352 | 176 Views | 17 Downloads
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How to cite this article:
Saumya Prasad, Pratima Mittal, Rekha Bharti and Jyotsna Suri. Correlation of vitamin D and Parathyroid hormone with insulin resistance in PCOS women. International Journal of Clinical Obstetrics and Gynaecology. 2020; 4(2): 348-352. DOI: 10.33545/gynae.2020.v4.i2f.548
International Journal of Clinical Obstetrics and Gynaecology