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International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2017, Vol. 1, Issue 1, Part A

Role of novel biomarker IL-6 in the prediction of pre-term labor
Author(s): Dr. Khushboo, Dr. Mriganka Mauli Saha, Dr. SC Biswas and GS Kamilya
Abstract: Objective: To evaluate the diagnostic value of maternal serum interleukin 6 (IL-6), for the prediction of preterm labor. Association of few major maternal high risk factors and occurrence of preterm labor was also studied.
Material and methods: Maternal serum IL-6 were prospectively determined in thirty patients in threatened preterm labor and thirty controls. Data was analyzed in study and control groups. Risk factors studied were - maternal age, socioeconomic status, parity, antenatal checkup, history of preterm labor in previous pregnancy, history of 2 or more spontaneous or induced abortion, vaginal infection.
Results: The strongest risk factor for preterm birth in our study is a previous preterm birth. In this study 60% mothers with history of preterm birth delivered preterm (p value - 0.05). Maternal serum IL-6 levels were significantly higher in the study group than controls. The IL-6 value associated with the highest percent of true positives and true negatives for the prediction of preterm labor was 5 pg/ml.
Conclusions: Maternal serum IL-6 is a reliable marker in the prediction and management of preterm labor and delivery.
Pages: 14-16 | 1114 Views | 400 Downloads
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How to cite this article:
Dr. Khushboo, Dr. Mriganka Mauli Saha, Dr. SC Biswas, GS Kamilya. Role of novel biomarker IL-6 in the prediction of pre-term labor. Int J Clin Obstet Gynaecol 2017;1(1):14-16.
International Journal of Clinical Obstetrics and Gynaecology