International Journal of Clinical Obstetrics and Gynaecology
2017, Vol. 1, Issue 1, Part A
Clinicopathological study of ovarian tumours in a tertiary care teaching institute
Author(s): Sathyavathi Ramadindi and Asma Mohammed Yousuf Ali
Abstract: This is a prospective study conducted in the Department of Obstetrics and Gynaecology. 87 cases of ovarian tumors were diagnosed during the 2 year study group. The incidence of ovarian tumors in the present study was 4.4%. Majority of women (68.8%) were in the age group 20-45 years with mean age (±SD) (39.1±9.88yrs). Malignant ovarian tumors were more common in multipara (71.4%).Commonest clinical presentation in ovarian tumors were pain abdomen (51.3% benign, 42.9% malignant) followed by mass per abdomen (25% benign, 28.7% malignant), dysmenorrhea (7.5% benign, 14.2% malignant) and urinary disturbances (7.5% benign, 14.2% malignant).Benign ovarian tumors were more common in premenopausal women (90%) and malignant ovarian tumors were seen in postmenopausal women (71.4%). In the present study USG findings revealed, 77.5% of benign ovarian tumors were <10 cms of size and 71.4% of malignant tumors were >10 cms of size. Septal thickness >3 mm seen in 3.6% of benign ovarian tumors and 57.1% in malignant tumors. Solid component was seen in 12.5% of benign ovarian tumors and 71.4% in malignant tumors. Ascites was seen in 57.1% of malignant ovarian tumors. The mean value of serum CA-125 is 37.2 U/ml among benign ovarian tumors and 119.14 U/ml among malignant tumors. The mean RMI value is 46.55 among benign ovarian tumors and 776.57 among malignant tumors. In benign ovarian tumors 57.5% were serous cyst adenoma and 27.5% were mucinous cyst adenoma. In malignant ovarian tumor 28.6% were serous cyst adenocarcinoma and 28.6% were granulosa cell tumor. Raised CA-125 value in postmenopausal women will suggest malignancy. RMI is calculated based on USG findings, CA-125 levels in postmenopausal women, which is a simple method to assess the risk of malignancy and to guide the patient to gynaecological oncologist for further management.
Sathyavathi Ramadindi, Asma Mohammed Yousuf Ali. Clinicopathological study of ovarian tumours in a tertiary care teaching institute. Int J Clin Obstet Gynaecol 2017;1(1):44-47. DOI: 10.33545/gynae.2017.v1.i1a.1561