Background: Vulvovaginal candidiasis (VVC) remains a common gynecological complaint, with increasing attention toward its potential association with systemic immune responses, including atopic skin disorders. Understanding this link may provide insights into host susceptibility and inform targeted management strategies.
Materials and Methods: This cross-sectional study was conducted in the Department of Obstetrics, Gouri Devi Institute of Medical Sciences and Hospital, Durgapur, West Bengal, from February 2016 to January 2017. A total of 150 women aged 18-45 years presenting with symptoms suggestive of VVC were evaluated. Clinical diagnosis was confirmed via microscopic examination and culture on Sabouraud dextrose agar. Dermatological history was assessed to identify coexisting atopic conditions such as atopic dermatitis, allergic rhinitis, and asthma. Statistical analysis included Chi-square test and logistic regression.
Results: Out of 150 symptomatic women, 94 (62.7%) were confirmed to have VVC. Among these, 38 (40.4%) reported a history of atopic disorders. The prevalence of VVC was significantly higher in women with atopic background compared to non-atopic individuals (p = 0.002). Candida albicans was the most common species isolated (71.3%). Logistic regression revealed that atopic skin conditions were independently associated with a 2.5-fold increased risk of VVC (95% CI: 1.3-4.7; p = 0.003).
Conclusion: There exists a significant association between vulvovaginal candidiasis and atopic skin disorders. Screening for atopic conditions in women presenting with recurrent or resistant VVC may be beneficial in clinical practice.
International Journal of Clinical Obstetrics and Gynaecology
Indexed in Index Copernicus
