Abstract: Background: The study aimed to evaluate the level of serum lipid profile in early second trimester (14-20weeks) and to investigate the relationship of lipid profile with development of hypertensive disorder of pregnancy.
Material and Methods: Serum Lipid profile (cholesterol, triglyceride, LDL, VLDL, and HDL) was measured by spectrophotometric principle by enzymatic colorimetric test with lipid clearing factor (LCF) in 140 pregnant women between 13-20 weeks of gestation.
Results: Out of 140 pregnant women, 21 cases developed hypertension with or without proteinuria and 119 remains normotensive. The total cholesterol, triglyceride, LDL, and VLDL levels was increased significantly in women who developed hypertensive disorder of pregnancy while HDL level was decreased.
Conclusion: So finally we conclude that the abnormal lipid profile in second trimester can be considered as an early, economical and noninvasive predictor of hypertensive disorder in pregnancy.
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