International Journal of Clinical Obstetrics and Gynaecology
2018, Vol. 2, Issue 3, Part C
Outcome of intravenous iron sucrose in treatment of anemia in pregnancy
Author(s): Shruti B Bhavi
Abstract: The objective of this study was to see the efficacy, safety and tolerability of intravenous iron sucrose in iron deficiency anemia during 14 to 34 weeks of pregnancy. A clinical trial was performed involving 56 patients attending the antenatal clinic at Shri B M Patil Medical College Hospital, Bijapur from October 2011 to August 2012, with hemoglobin levels between 70-110g/L and serum ferritin of < 15 ng/ml. Iron sucrose was administered as 200 mg in 100 ml 0.9% sodium chloride per day. The primary outcome measures for the trial, haemoglobin and serum ferritin levels were measured after 4 weeks. The change in haemoglobin in women receiving intravenous iron was higher 22 ±11.5 g/L (p<0.0001). Similarly the change of serum ferritin was significantly higher in women receiving intravenous iron. 55% of participants had an improvement in haemoglobin more than 20 g/L. 48% of patients showed increase in ferritin level between 51 to 100 ng/ml. Intravenous iron sucrose is more effective in correction of anemia and increasing maternal iron stores.