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International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2018, Vol. 2, Issue 4, Part A

Hospital based study of prognostic factor of endometrial cancer patients
Author(s): Dr. Jaya Kumari, Dr. Sangeeta Pankaj, Dr. Rakesh Ranjan kumar and Dr. Vijayanand Choudhary
Abstract: Background:Endometrial cancer (EC) is the sixth most common cancer in women worldwide (fourteenth most common cancer overall), with 320,000 new cases diagnosed in 2012 [1]. The declining trend of cervical cancer and the predicted rise of endometrial cancer in India means that endometrial cancer will be a significant issue in India. We studied and analyzed the demographics, staging, treatment details, and outcomes of operated cases of endometrial cancers.
Material and Methods: This is a retrospective study carried out at IGIMS, from 2008 to 2017. All patients of histopathologically proven endometrialcancer operated in the department during this period were studied and analysed.
Results: In our study we found 46 ECpatients with a median ageof 58 years (40-70 years).41 patients had postmenopausal bleeding and rest 5 had complains of discharge per vagina.41 patients were found to have lesion limited to less than half of myometrium and no lymph node involvement and so were not given any adjuvant therapy. 5 patients required adjuvant therapy following surgery. The pathological stages were Stage IA in 28 patients, Stage IB in 10 patients, Stage II in 4 patients, Stage IIIC1 in 3 patients, Stage IIIC2 in 1patient. Grade 1 tumor were seen in 23 patients, Grade 2 in 13 patients, and Grade 3 in 10 patients. With a median follow up of 5 year OS was 86.84%. Age >60 years, Stage III or greater, and non endometroid adenocarcinoma were independent prognostic factors that adversely affected overall survival (OS).
Conclusions: Prognosis of patients with endometrial cancer is good as they become symptomatic in early stage and hence are diagnosed and treated early as compare to ovarian and cervical cancer. However, elderly status, higher stage, and a poorly differentiated tumor are associated with poor outcomes in endometrial cancer.
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How to cite this article:
Dr. Jaya Kumari, Dr. Sangeeta Pankaj, Dr. Rakesh Ranjan kumar, Dr. Vijayanand Choudhary. Hospital based study of prognostic factor of endometrial cancer patients. Int J Clin Obstet Gynaecol 2018;2(4):09-12.
International Journal of Clinical Obstetrics and Gynaecology