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International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2019, Vol. 3, Issue 1, Part C

Transient hyperthyroidism in hyperemesis gravidarum
Author(s): Dr. Mangal Puri, Dr. Divya Punetha, Dr. Monica Maan and Dr. Shankar Burute
Abstract:
Physiologically there is Increased thyroid activity due to increase in circulating levels of thyroid binding globulin (TBG) in response to estrogen, with increase in the bound portion of thyroid hormone and due to thyrotropic substances secreted by the placenta. Contributors are placental chorionic thyrotropin and HCG. These patients have higher levels of HCG and transient hyperthyroidism which decides the severity of hyperemesis.
Data collected from patients with hyperemesis gravidarum and antenatal patients with morning sickness from our hospital. Total sample size is 200, 100 cases and 100 controls. It is a prospective study and the period of study is July 2016 to sept 2018. The patients are investigated for serum T3, T4, TSH and beta HCG level correlation.
Hyperthyroidism associated with hyperemesis gravidarum is of a transient nature where serum T3 and serum T4 levels are elevated between 8-14 weeks of gestation and normalize by 18-20 weeks of gestation without anti‐thyroid treatment. We need to treat these patients diagnostically in a supportive manner.

Pages: 131-135 | 1072 Views | 262 Downloads
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How to cite this article:
Dr. Mangal Puri, Dr. Divya Punetha, Dr. Monica Maan, Dr. Shankar Burute. Transient hyperthyroidism in hyperemesis gravidarum. Int J Clin Obstet Gynaecol 2019;3(1):131-135. DOI: 10.33545/gynae.2019.v3.i1c.22
International Journal of Clinical Obstetrics and Gynaecology