Abstract: Aim: To study the effects of maternal and fetal outcomes in case of thyroid dysfunction, specifically hypothyroidism.
Methods: The studied subjects included all pregnant women reporting to the hospital for a period of one year. All participants were subjected to detailed history, thorough general physical, systemic, local examinations, and routine investigations, thyroid function tests (serum TSH, T3, T4). All participants were divided into two groups, group-I: pregnant women diagnosed with hypothyroidism, group-II: euthyroid pregnant women (control group). Maternal and fetal outcomes of subjects in both groups were confirmed.
Results: A total of 10045pregnant women who attended OPD were qualified after applying exclusion criteria. Out of these, 9627 pregnant women were found euthyroid and hypothyroidism was identified in 408 (4.05%) women. Statistically, maternal outcomes like gestational hypertension, PROM, preterm premature rupture of membrane and placental abruption were found to be highly significant. (p<0.01).
Conclusions: Early detection and treatment of women with hypothyroidism in early pregnancy will improve the perinatal outcome.
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