Abstract: Introduction: The purpose of the study was to prospectively evaluate and compare maternal and perinatal outcome of pregnant women who were diagnosed hypothyroid during pregnancy. Pregnancy has a huge impact on the thyroid function in both healthy women as well as those with thyroid dysfunction.
Aims and Objectives: To find out the measurement of serum T3, T4 and TSH at first antenatal visit and to find out the correlation of hypothyroidism with maternal and perinatal outcome.
Materials and Methods: This study was done among pregnant women who came for first antenatal checkup, attending the OPD of Department of Obstetrics and Gynaecology at Sree Mookambika Institute of Medical Sciences, kulasekharam. Measurement of serum free T3, T4 and TSH were determined at first antenatal checkup. Outcome was measured in terms of preeclampsia, mode of delivery, low birth weight and NICU admissions.
Results: Majority of the hypothyroid subjects were delivered by LSCS and it was found to be significant (p=0.03). In our study 6.1% of the babies got admitted in NICU which is considered significant. In this study it was found that, majority of the hypothyroid mothers had preeclampsia and there was no significant association between preeclampsia and thyroid levels (p>0.05).
Conclusion: Maternal hypothyroidism is a disorder with great potential to adversely affect maternal and fetal outcomes. Maternal effects are preeclampsia, operative deliveries, gestational hypertension, anaemia, preterm delivery and placental abruption. Fetal adverse effects are low birth weight, NICU admission and prematurity. Since hypothyroidism is easily treated, timely detection and treatment could decrease maternal and perinatal outcome. So we recommend routine screening for thyroid dysfunctions in pregnancy.
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