International Journal of Clinical Obstetrics and Gynaecology
2019, Vol. 3, Issue 4, Part C
Predictors of nausea and vomiting risk factors and its relation to anesthesia
Author(s): Shahla Muthana Khlil-Fahmi and Ban Asad Hussein
Abstract: This is the first study to investigate risk factors for PONV after xenon-based anesthesia. While the incidence of PONV was significantly lower than predicted by Apfel Score, female sex, young age, and long duration of anesthesia predicted PONV after xenon-based anesthesia. A history of PONV or non-smoking status failed to reach statistical significance, probably because of lower power associated with smaller effect size. The lack of efficacy of 5-HT3 receptor antagonists is reasonable because xenon antagonizes these receptors itself, yet needs to be interpreted carefully and warrants confirmation by a sufficiently powered randomized controlled study.
Shahla Muthana Khlil-Fahmi, Ban Asad Hussein. Predictors of nausea and vomiting risk factors and its relation to anesthesia. Int J Clin Obstet Gynaecol 2019;3(4):148-153. DOI: 10.33545/gynae.2019.v3.i4c.305