Labour induction is one of the most common procedure in obstetrics .Oxytocin is one of the time tested drug, but certain disadvantages associated with oxytocin can be countered by using misoprostol as labour inducing agent.
Objectives: 1. To know the efficacy of oral Misoprostol solution in inducing labour 2. To calculate the induction delivery interval 3.To know the maternal and fetal outcome in the study population.
Methodology: A prospective observational hospital based study involving 200 term pregnant patients getting admitted to the labour ward. All of them were induced with oral misoprostol in solution form at a static dose regimen, second hourly (20 ug) for a total of five doses. Labour monitored as per the labour room protocol, reassessed after five doses or earlier as per clinical progress.
Results: 200 patients were included, the efficacy of its use was excellent, mean number of doses required was 5, with the average induction delivery interval of 13.65 hrs, with 77.5% of vaginal delivery rate and 22.5% of caesarean rate, 30% needed oxytocin augmentation and 6.5% of the babies had meconium staining of liquor, of them 23.08% showed signs of meconium aspiration syndrome and one perinatal death was noted in the study.
Conclusion: Oral misoprostol solution in static dosage is a simple, safe and effective method for induction of labour at term.