Abstract: Background: Uterine fibroids are one of the most common benign uterine tumors seen in females of reproductive age group. The present study was conducted to compare efficacy of Mifepristone and Ulipristal acetate in the management of symptomatic uterine fibroids.
Materials & Methods: The present study was conducted on 80 women with diagnosis of uterine fibroid. Patients were divided into 2 groups of 40 each. Group I patients were given mifepristone 25 mg orally and group II patients received Ulipristal acetate 10 mg.
Results: There were 28 patients in group I and 25 in group II with size less than 3 cm and 12 in group I and 15 in group II with size 3-5 cm. The difference was significant (P<0.05). There was significant reduction in size more in group II patients with size less than 3 cm as compared to group I patients. There was more percentage of patients in group II having reduction in pain and menorrhagia as compared to group II. However, the difference was non- significant (P>0.05).
Conclusion: Authors found that both the agents can be used in management of women with uterine fibroids.
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