Ovulatory disorders are the leading cause of female infertility. Infertility is age- related decline in fertility. Antral follicular count (AFC) is a reliable marker to assess female fecundity. This study was designed to evaluate the relationship of AFC with age in sub-fertile cases and with healthy (fertility proven) control women.
Materials and Methods: A total of 50 infertile females attending investigation of subfertility and age, sex-matched 50 healthy control subjects were recruited. On 2nd or 3rd day of the ovarian cycle, the basal ovarian volume and AFC were measured by endovaginal ultrasound. Transvaginal USG was carried out on the second and third day of the menstrual cycle.
Results: The mean total ovarian volume in cases was 11.25 and in controls 11.67. The mean antral follicular count in cases was 6.95±1.85, while in controls 10.44±2.01. There was an inverse correlation between age and antral follicular count (r = -0.424 with p value 0.002). While there was no significant correlation between ovarian volume and antral follicular count (r = -0.318 with p value 0.352).
Conclusion: The ovarian volume has no role as a biomarker of ovarian reserve. AFC has been proved significantly as an excellent predictor of ovarian reserve and response when compared to other parameters