Abstract: Synchronous primary malignancies account for 0.7-1.8% of all gynecologic tumors. Synchronous endometrial and ovarian cancer (SEOC) is more frequent in younger, obese, premenopausal and nulliparous women. Organ-confined and low-grade synchronous endometrial and ovarian tumors (SEOs) clinically behave as independent primary tumors rather than a single advanced-stage carcinoma and have a better prognosis.
However differentiation between 1) primary ovarian tumor metastasizing to endometrium, 2) primary endometrial cancer metastasizing to ovary and 3) primary synchronous tumors of both endometrium and ovary is important as the management and prognosis is variable in all cases.
We here present a case of a 50 yr postmenopausal female presented with bleeding, diagnosed as endometrial adenocarcinoma on biopsy with no other organ involvement on imaging, underwent exploratory laparotomy with TAH with BSO with pelvic lymphadenectomy. On histopathology was diagnosed as endometrial adenocarcinoma with ovarian involvement, making a diagnosis to advanced stage endometrial cancer. On Immuno-histochemistry (IHC) was found to be synchronous primary ovarian and endometrial carcinoma stage 1, with no further treatment the patient was being followed up and is doing fairly well.
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