International Journal of Clinical Obstetrics and Gynaecology

Background: Uterine fibroids are among the most common benign tumors affecting women of reproductive age. Surgical intervention is often indicated in symptomatic cases, with myomectomy as the preferred fertility-sparing procedure. With the advancement of minimally invasive techniques, laparoscopic myomectomy has gained popularity. However, comparative outcomes between laparoscopic and open approaches remain clinically relevant, particularly in terms of intraoperative complications, postoperative recovery, and fertility outcomes.

Materials and Methods: This prospective comparative study was conducted at the Department of Gynaecology, Mayo Institute of Medical Sciences, Lucknow, from March 2019 to February 2020. A total of 120 reproductive-age women with symptomatic uterine fibroids were included, with 60 undergoing laparoscopic myomectomy and 60 undergoing open myomectomy. Intraoperative blood loss, operative time, hospital stay duration, postoperative pain scores, and complication rates were recorded. Statistical analyses included Chi-square test, unpaired t-test, and Mann-Whitney U test where appropriate.

Results: Mean operative time was longer in the laparoscopic group (108.2 ± 14.5 min) versus the open group (92.4 ± 12.3 min; p < 0.001), but laparoscopic surgery resulted in significantly lower blood loss (134.6 ± 24.1 mL vs 241.8 ± 30.6 mL; p < 0.001), shorter hospital stay (2.1 ± 0.6 days’ vs 4.8 ± 1.2 days; p < 0.001), and reduced postoperative pain scores (3.2 ± 0.9 vs 6.1 ± 1.1; p < 0.001). Complication rates were lower in the laparoscopic group.