Abstract: Background: Ovarian cancer is the leading cause of mortality among gynecological malignancies. To date there is no single test with accurate sensitivity and specificity in the pre operative prediction of ovarian malignancy.
Objective: To evaluate the role of IOTA (International Ovarian Tumor Anlaysis) simple ultrasound rules in the pre operative prediction of ovarian malignancy and to correlate IOTA predictions with histopathology reports.
Methods: A prospective study was conducted on 50 patients with complex adnexal masses detected sonologically and planned for surgery in Father Muller Medical College Hospital, Mangalore. Based on ultrasonographic findings IOTA simple ultrasound rules were applied and preoperative prediction was compared with the final histopathology report.
Results: Sixty percentage of patients had benign masses, 8 % had borderline masses and 32 % had malignant masses. In our study IOTA had a sensitivity of 100%, specificity of 92.31 %, PPV of 87.5 %, NPV of 100% and diagnostic accuracy of 95%.
Conclusion: IOTA simple rules using ultrasonography has increased diagnostic accuracy and would serve as an excellent non invasive screening modality and as an diagnostic tool in predicting ovarian malignancy.
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