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International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2020, Vol. 4, Issue 6, Part C

Comparison of efficacy of different modes of induction in predicting the outcome of labour: A randomized controlled trial
Author(s): Vasanthi Balamurugan, Kurian Joseph, Rekha Kurian and Tarun Joseph
Abstract: Aim: To Compare the efficacy of PGE2 gel (Prostaglandin E2 gel), oral misoprostol and combination group (Foleys bulb + oral misoprostol) in predicting the outcome of induction of labour.
Materials and Methods: This prospective randomized controlled trial included 300 women requiring induction of labour. A total of 101 women were randomly allocated to PGE2 gel group, 99 women to oral misoprostol group, 100 women allocated to the combination group using computer generated allocation sequence. The primary outcomes which was analysed in the study were time interval between induction and active phase of labour and time interval between induction and delivery.
Results: The mean time interval between induction and active phase of labour was shorter with combination group compared to the prostaglandin E2 group & oral misoprostol group (8hrs vs 11hrs vs 13hrs, p value 0.004). The combination group and the prostaglandin E2 had almost the same shorter time interval between induction and delivery (17hrs vs 17hrs vs 20hrs, p value 0.104). No significant difference was observed with regard to maternal and neonatal outcomes.
Conclusion: In our study, the combination group achieved shorter time interval between induction and active phase of labour, while combination group and PGE2 gel group had almost similar time interval between induction and delivery and also higher number of vaginal deliveries compared to oral misoprostol group without increasing labour complications.
Pages: 139-142 | 128 Views | 56 Downloads
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How to cite this article:
Vasanthi Balamurugan, Kurian Joseph, Rekha Kurian, Tarun Joseph. Comparison of efficacy of different modes of induction in predicting the outcome of labour: A randomized controlled trial. Int J Clin Obstet Gynaecol 2020;4(6):139-142. DOI: 10.33545/gynae.2020.v4.i6c.744
International Journal of Clinical Obstetrics and Gynaecology