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International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2020, Vol. 4, Issue 6, Part C

Second trimester umbilical artery Doppler in the prediction of adverse pregnancy outcomes in a low risk population: A prospective observational study
Author(s): Adeyemi Sunday Adefisan, Akinyemi Akinsoji Akintayo, Jacob Olumuyiwa Awoleke, Anthony Awolowo Thomas, Olusola Peter Aduloju, Babatunde Ajayi Olofinbiyi and Oluwatoyin Olawumi Adefisan
Abstract: Introduction: Pregnancies with sustained high resistance uteroplacental circulation have been reported to be at significant risk of adverse outcomes. Assessment of fetoplacental circulation non-invasively using umbilical artery Doppler velocimetry has been suggested as a tool for prediction of perinatal outcomes.
Objectives: To determine the utility of second trimester umbilical artery Doppler velocimetry in the prediction of adverse perinatal outcomes (intrauterine growth restriction (IUGR), low birth weight (LBW) and stillbirth).
Methods: One hundred and twenty low-risk nulliparous women with viable singleton pregnancies who met the inclusion criteria had umbilical artery Doppler assessment between 22 and 26 weeks gestation. RI≤ 0.76, PI≤ 1.36 and SD ≤ 4.52 were considered as normal. Each participant was monitored till delivery to assess outcome. Diagnostic performance of the Doppler indices for the prediction of adverse pregnancy outcomes were determined.
Results: Thirteen (10.8%) women had at least one abnormal Doppler index, abnormal RI was recorded in 1(0.83%) woman, 12(10.0%) had abnormal PI while none had abnormal SD ratio. 50/120 (42%) women had at least one adverse outcome. The sensitivity and specificity of RI for IUGR, LBW and stillbirth were 0.0%, and 99.1%, 0.0% and 98.9% and 0.0% and 99.1% respectively. For IUGR the sensitivity and specificity of PI were 0.0% and 88.8% respectively, while PI had 12.0% sensitivity and specificity of 90.5% for LBW. For stillbirth, the sensitivity and specificity of PI were 66.7% and 91.5%.
Conclusion: Late second trimester umbilical artery Doppler velocimetry has a limited role in this low risk population for prediction of adverse pregnancy outcomes. The role of umbilical artery Doppler velocimetry in the prediction of adverse outcomes in high-risk pregnant women may be worthwhile.
Pages: 167-173 | 95 Views | 37 Downloads
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How to cite this article:
Adeyemi Sunday Adefisan, Akinyemi Akinsoji Akintayo, Jacob Olumuyiwa Awoleke, Anthony Awolowo Thomas, Olusola Peter Aduloju, Babatunde Ajayi Olofinbiyi, Oluwatoyin Olawumi Adefisan. Second trimester umbilical artery Doppler in the prediction of adverse pregnancy outcomes in a low risk population: A prospective observational study. Int J Clin Obstet Gynaecol 2020;4(6):167-173. DOI: 10.33545/gynae.2020.v4.i6c.750
International Journal of Clinical Obstetrics and Gynaecology