Abstract: Background: The present study was conducted to assess the effect of the infusion of lignocaine on the bispectral index in patients undergoing caesarean section under spinal anaesthesia.
Materials and Methods: 104 female patients age ranged 18-40 years with ASA physical status of I or II scheduled for elective caesarean section under spinal anaesthesia were recruited. Patients were divided into 2 groups of 52 each. Group I received intravenous 1.5 mg/kg of lignocaine bolus and group II patients were given 0.9% sodium chloride. The changes of Sao2, BIS and adverse effects were recorded.
Results: The mean age of patients in group I was 34.5 years and in group II was 30.8 years, weight was 65.2 kgs and in group II was 66.1 kgs and duration of surgery was 82.3 minutes and in group II was 85.1 minutes. BIS index in group I was significantly less at 30 minutes, 40 minutes, 50 minutes, 60 minutes (P< 0.05) as compared to group II. Common side effects in group I was shivering seen in 3 and 4 in group II, nausea 5 in group I and 6 in group II and ephedrine requirement seen 2 in group I and 3 in group II.
Conclusion: Intravenous lignocaine infusion given with spinal anaesthesia in females undergoing elective caesarean delivery provided lower BIS values as compared to normal saline group.