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International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2021, Vol. 5, Issue 1, Part C

Diagnostic accuracy of spot albumin creatinine ratio and its association with neonatal and maternal outcome in preeclampsia: Prospective analysis at a rural tertiary care centre
Author(s): Deepika Kapil, Ajay Sood, Anju Vij, Seema Sharma, Amit Gupta, Rajendra Kumar and Uday Mahajan
Abstract: Spot urinary ACR detection of proteinuria has been recommended to screen pre-eclampsia during pregnancy.
Objective: Assessment of diagnostic accuracy of spot ACR and its association with neonatal and maternal outcome in preeclampsia.
Methods: Eighty pregnant women who reported to the antenatal OPD at 17-20 weeks of period of gestation were enrolled in the study over the period of one year from Jan 2018 to Dec 2018 at Department of Obstetrics & Gynaecology Dr Rajendra Prasad Govt. Medical College, Kangra at Tanda, Himachal Pradesh, India. Preeclampsia was defined as per NHBPEP2000 working group, resting hypertension >140/90 mmHg after 20th weeks of pregnancy.
Results: Prevalence of pre-eclampsia was 10%. Women with pre-eclampsia were significantly older than normotensive women (P=0.014). Incidence of pedal edema and abdominal edema was significant higher in the women with pre-eclampsia (P<0.05). 75% of pre-eclampsia women delivered neonates with low birth weight (P=0.044). Spot ACR was significantly higher in the women with pre-eclampsia in comparison to normotensive women (0.4 [0.22, 2.1] vs. 0.12 [0.1, 0.3]; P=0.003). Cut-off of spot ACR (>0.3), sensitivity and specificity were 62.5% and 79.2% while positive predictive value and negative predictive value were 25% and 90%. Diagnostic accuracy of spot ACR for detection of pre-eclampsia was 77.5%.
Conclusion: ACR could be very useful test for predicting the development of preeclampsia, maternal as well as neonatal outcomes.
Pages: 141-144 | 115 Views | 66 Downloads
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How to cite this article:
Deepika Kapil, Ajay Sood, Anju Vij, Seema Sharma, Amit Gupta, Rajendra Kumar, Uday Mahajan. Diagnostic accuracy of spot albumin creatinine ratio and its association with neonatal and maternal outcome in preeclampsia: Prospective analysis at a rural tertiary care centre. Int J Clin Obstet Gynaecol 2021;5(1):141-144. DOI: 10.33545/gynae.2021.v5.i1c.804
International Journal of Clinical Obstetrics and Gynaecology