Pre-eclampsia is a significant co-morbidity which can have adverse effect on maternal and neonatal outcomes. Recent evidence have suggested that there is a causal association between low levels of vitamin D and development of pre-eclampsia in nulliparous women.
Aims and Objectives: To evaluate prevalence of pre-eclampsia in Vitamin D supplemented and non supplemented primigravida mothers.
Materials and Methods: A total of 100 primigravida mothers were recruited in the study and divided in to two groups of 50 subjects each. The recruitment was done prior to 20 weeks of gestation wherein 50 patients of interventional group received Vitamin D supplements along with regular antenatal care. Rest 50 patients received only the regular antenatal care.
Results: At baseline, hypovitaminosis D in interventional group was noted to be 40% (n=20). A total of 2 patients developed pre-eclampsia in interventional group whereas 9 patients developed pre-eclampsia in control group. The difference was significant with a higher prevalence of pre-eclampsia in control group that did not receive vitamin D supplementation.
Conclusion: Vitamin D supplementation should be considered as an essential component in antenatal care which can be associated with lowering the incidence of pre-eclampsia.