Abstract: Background: Endometrial thickening is a commonly measured parameter on routine gynecological ultrasound and magnetic resonance image. Recent studies show there is a relation between vitamin D (vit D), obesity and the degree of endometrial thickness.
Aim of the study: To assess the relation between Vit (D) level and body mass index with post-menopausal endometrium thickness.
Patients and Method: A cross sectional study that carried out in Department of Obstetrics and Gynecology at Baghdad Teaching Hospital from the first of Jan 2020 to the end of Dec 2020. A sample of 100 post-menopausal women participated in the study after fulfilling inclusion criteria (Menopause for 12 months, endometrial thickness ≥5 mm) for each patient we did for her pelvic ultrasound for endometrial thickness, measure Vit (D) level and body mass index. The patients were divided into: - patients who had post-menopausal bleeding we did endometrial biopsy and sent for histopathology depending on the result subdivided into group I with malignant changes and group II without malignant changes and group III = patients without Vaginal bleeding.
Results: Endometrial thickness in group I was (16.15 ± 8.4) for group II was (14.3 ± 7) and for group III with significant difference found (P = 0.02), BMI were represented in group I (37.25 ± 5.15), (30.6 ± 8) for group II and (31.63 ± 7.47) in group III with no significant difference (P = 0.3), on logistic regression between these parameters and (ET) the result was significant with (vit D) with (p value = 0.02).
Conclusion: Vitamin (D) level inversely related for post-menopausal endometrial thickness, post-menopausal bleeding and probability of endometrial cancer.