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International Journal of Clinical Obstetrics and Gynaecology

International Journal of Clinical Obstetrics and Gynaecology

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Print ISSN: 2522-6614, Online ISSN: 2522-6622

International Journal of Clinical Obstetrics and Gynaecology

2021, Vol. 5, Issue 4, Part C

Levothyroxine replacement in subclinical hypothyroidism during pregnancy and its effect on fetomaternal outcome
Author(s): Dr. Gayatri Mathuriya and Dr. Shivangi Panday
Abstract: Background: We aimed to study improvement in feto-maternal outcome in pregnant women with subclinical hypothyroidism treated with levothyroxine therapy.
Methodology: This was prospective comparative study, on antenatal Women who had first trimester thyroid function tests at our Hospital. All female were categorized into three groups (Group A- TSH level>2.5-4 μIU/l receiving levothyroxine treatment; group B- TSH level between 4.1-10 μIU/l receiving levothyroxine treatment and Group C- women with TSH level >2.5-4 μIU/l not receiving levothyroxine treatment). Fetomaternal outcome was assessed between the groups.
Results: We observed no significant difference in maternal outcome between three groups but APGAR score was significantly lower in group B as compared to other two groups (p<0.05).
Conclusion: Levothyroxine replacement therapy is safe and effective in case of subclinical and overt hypothyroidism & in SCH pregnancy loss in mother & neonatal admission rate to NICU shows a significant decrease on levothyroxine administration.
Pages: 173-177 | 94 Views | 32 Downloads
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How to cite this article:
Dr. Gayatri Mathuriya, Dr. Shivangi Panday. Levothyroxine replacement in subclinical hypothyroidism during pregnancy and its effect on fetomaternal outcome. Int J Clin Obstet Gynaecol 2021;5(4):173-177. DOI: 10.33545/gynae.2021.v5.i4c.982
International Journal of Clinical Obstetrics and Gynaecology