International Journal of Clinical Obstetrics and Gynaecology
2021, Vol. 5, Issue 5, Part A
Assessment of role of serum uric acid as a predictor of gestational diabetes mellitus
Author(s): Dr. Lavee Mehrotra and Dr. Seema Mishra
Abstract: Background: Gestational diabetes mellitus (GDM) is diabetes or glucose intolerance that is primarily detected during pregnancy. The present study was conducted to assess the role of serum uric acid as a predictor of gestational diabetes mellitus. Materials & Methods: 78 antenatal women in first trimester were enrolled. Venous blood sample was taken from all patients and serum uric acid was measured by colorimetric assay with detection limit of 0.2-20 mg/dl and patients were followed up at 24-28 weeks to do oral glucose tolerance test. Results: Age group 20-25 years had 14, 26-30 years had 26, 31-35 years had 18 and 36-40 years had 10 patients. Parity was multipara in 42 and primi in 36. Serum uric acid was elevated (>4.2) in 28 and normal (<4.2) in 50. GTT result was normal in 68 and positive in 10 patients. Among 28 elevated uric acid patients, 4 had positive GTT results and among 50 normal serum uric acid patients, 6 had positive GTT result. Conclusion: There was increase in the risk of development of GDM with increased levels of serum uric acid in the first trimester.
Dr. Lavee Mehrotra, Dr. Seema Mishra. Assessment of role of serum uric acid as a predictor of gestational diabetes mellitus. Int J Clin Obstet Gynaecol 2021;5(5):33-35. DOI: 10.33545/gynae.2021.v5.i5a.1012