Background: Endometrial receptivity plays a pivotal role in successful embryo implantation in assisted reproductive techniques (ART). Among various markers, endometrial thickness (EMT) measured via transvaginal ultrasound is considered a non-invasive indicator of uterine preparedness. This study explores the association between EMT and clinical pregnancy outcomes in women undergoing ART.
Materials and Methods: This prospective observational study was conducted in the Department of Obstetrics, Viswabharathi Medical College and Hospital, Kurnool, from October 2020 to September 2021. A total of 180 women undergoing ART cycles were enrolled. EMT was measured on the day of trigger using transvaginal ultrasound. Participants were categorized into three groups: Group A (EMT <7 mm), Group B (7-10 mm), and Group C (>10 mm). Pregnancy outcomes including biochemical pregnancy, clinical pregnancy, and ongoing pregnancy were evaluated. Statistical analysis included Chi-square test and ANOVA with p<0.05 considered significant.
Results: Among 180 patients, the clinical pregnancy rate was significantly higher in Group C (44.1%) compared to Group B (29.7%) and Group A (13.3%). Mean EMT in pregnant women was 10.8±1.4 mm, whereas in non-pregnant women it was 8.2±1.9 mm (p<0.001). A positive linear correlation (r = 0.52) was observed between EMT and pregnancy outcome.
Conclusion: This study demonstrates a significant association between increased endometrial thickness and higher pregnancy success rates in ART. EMT measurement on the day of trigger can serve as a valuable non-invasive predictor for optimizing embryo transfer timing and improving reproductive outcomes.