The prevalence of type 2 diabetes and moderate fasting hyperglycemia is high in Guinea, while data on gestational diabetes are scarce. Objective: To determine the prevalence of Gestational Diabetes among women admitted for prenatal consultation, identify their socio-epidemiological characteristics and any associated risk factors. Patients and Methods: Prospective study conducted in pregnant women who came for prenatal follow-up in two urban health centers in the prefecture of Kindia, Guinea during the period from January 1 to June 30, 2018, screened according to the recommendations of International Association of Diabetes and Pregnancy Study Group (IADPSG). A single abnormal value is sufficient to make the diagnosis of GDM. All pregnant women between 24 and 28 SA were included. Women with multiple pregnancies and/or pre-existing diabetes or refusal to participate in the study were excluded. The variables analyzed: maternal age, gestational age, parity and exposure or not to risk factors. The data were analyzed by specific statistical tests with a probability p<0.05. Results: Seven hundred and forty-two (742) pregnant women were screened with 103 cases of GDM diagnosed, representing a prevalence of 13.8%. The epidemiological profile of women with GDM was dominated by the average maternal age which was 28.7 ± 6.5 years, housewives 57.28% (59/103), no level of education 53.39% (55/ 103), married 67.96% (70/103) with an average parity of 2.11± 1.9. The average gestational age was 27.1 ± 5.6 SA. The risk factors were dominated by advanced maternal age, with a proportion of 70.27% and 13.41% of patients without risk factors, screening for GDM was positive (P < 0.000001). Conclusion: The GDM is frequent among the women followed at the prenatal consultation in Kindia. Systematic screening integrated with prenatal care remains the best means of prevention.