Abstract: Background: The procedures for assisted reproductive technologies (ART) are constantly advancing to improve conception rates, reduce the occurrence of multiple births, and ensure the delivery of healthy children from individuals with genetic conditions. This study set out to assess the parameters of three-dimensional ultrasonography and power Doppler angiography (3D US-PDA). as a possible pregnancy predictorsand implantation markers on day of human chorionic gonadotropin (hCG) injection in an intracytoplasmic sperm injection (ICSI) and embryo transfer program.
Methods: 40 patients, ranging in age from 25 to 40, participated in this prospective study, females, with normal basal follicle-stimulating hormone (FSH) level (<10 mUI/mL), good quality embryos and infertility is due to male factor or tubal factor undergoing ICSI. Induction of ovulation [All participants in this trial underwent ovarian stimulation using an oral contraceptive pill regimen consisting of 0.1 mg of Decapeptyl with human menopausal gonadotrophin.] are assed to all patients.
Results: The area under the curve (AUC) for 3D US-PDA parameters was statistically significant; however, their values for predicting endometrial receptivity in ICSI were only suggestive and not conclusive. Patients with endometrial volume (EV) greater than or equal to 5 ml had a group application with 80% sensitivity and 64% specificity; an individual application had a predictive negative value of 84.2% and a predictive positive value of 57.1%. The values of EV, Flow Index (FI), Vascularization index (VI), and Vascularization FI were notably diminished in the group that was not pregnant compared to the group that was expectant.
Conclusions: When evaluating endometrial receptivity in IVF/ICSI and embryo transfer cycles, 3D US-PDA is a helpful test. Pregnancy can be predicted using the EV and 3D power Doppler indexes on the day of hCG injection, particularly if no grade 1 or just one grade 1 embryo is to be transferred.
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