International Journal of Clinical Obstetrics and Gynaecology
2023, Vol. 7, Issue 1, Part A
Prolactin and its correlation with gestational age and birth weight in a new-born
Author(s): Jean Sarah Paul and Nishita Shettian
Abstract: Prolactin is analogous in certain respects to growth hormone and its role in growth and development of the fetus in utero is steadily emerging. It can serve as a predictor of fetal maturity in utero. Our objective was to study the correlation between Serum Cord Prolactin levels with birth weight and gestational age in antenatal cases. It was a prospective study enrolling 280 eligible pregnant women presenting to the labour room in a tertiary hospital. Umbilical cord serum prolactin was assayed by Chemiluminescent Micro particle Immunoassay and was correlated with gestational age and birth weight of the neonate. 76.1% were term neonates. 49.3% were born to mothers with high risk pregnancies. Mean serum prolactin was higher in neonates of <28 weeks (686 ng/ml) but was almost similar from 28 weeks to term with p value of 0.537. Mean serum prolactin was 493.70 ng/ml for low birth weight neonates and p value was 0.754. There was no statistically significant correlation between prolactin with birth weight and gestational age in our study but can open an arena for research in the future.
Jean Sarah Paul, Nishita Shettian. Prolactin and its correlation with gestational age and birth weight in a new-born. Int J Clin Obstet Gynaecol 2023;7(1):33-35. DOI: 10.33545/gynae.2023.v7.i1a.1251
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