International Journal of Clinical Obstetrics and Gynaecology
2023, Vol. 7, Issue 6, Part B
Fulminating pre-eclampsia at approximately 15 weeks gestation: A case report
Author(s): Dr. Hannah Darling, Dr. Emily Penney, Dr. Tina Kapoor and Dr. Surajit Das
Abstract: Pre-eclampsia is currently defined as new-onset of hypertension occurring after 20 weeks gestation, with significant proteinuria or maternal end organ dysfunction. The exact pathophysiology remains uncertain however it has been hypothesised that anti-angiogenic factors arising from the developing placenta contribute to its development. This case report describes the presentation of a 37 year old patient clinically presenting with pre-eclampsia at 15 weeks gestation. A literature review revealed 5 previously reported similar cases, indicating the need for better understanding of the pathophysiology and awareness of the condition at early gestations. We explore the possible differential diagnosis of haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura and discuss the reasoning for the definitive diagnosis of fulminating early onset pre-eclampsia.
Dr. Hannah Darling, Dr. Emily Penney, Dr. Tina Kapoor, Dr. Surajit Das. Fulminating pre-eclampsia at approximately 15 weeks gestation: A case report. Int J Clin Obstet Gynaecol 2023;7(6):92-94. DOI: 10.33545/gynae.2023.v7.i6b.1403
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