Abstract: Background: The main objective of the study is to evaluate the risk and pregnancy outcomes of Gestational Diabetes mellitus in women with previous history of Polycystic Ovarian Syndrome as compared to antenatal women without previous history.
Methods: This is a case-control (observational) study conducted in Government Chengalpattu Medical College and Hospital, Chengalpattu in Obstetrics and Gynecology department, Tamil Nadu. All antenatal women attending the outpatient or labour room with Polycystic Ovarian Syndrome who satisfy the criteria were included and studied for development of gestational diabetes, pregnancy outcomes, associated conditions as compared to antenatal women without previous history of Polycystic Ovarian Syndrome.
Results: Out of 112 in our study population, 56 belonged to antenatal women with Polycystic Ovarian Syndrome and 56 belonged to normal pregnant women. In this study, about 42% of the Polycystic group developed Gestational Diabetes which is statistically significant as compared to 12.5% in normal pregnant group. Among the Polycystic group, 67% had conceived spontaneously, while 88% in normal group had spontaneous conception. Among the Polycystic group, 16% conceived by Artificially Reproductive Technique which is statistically significant, while 7% in normal group have conceived through Artificial Reproductive Technique. While studying the maternal outcome in the Polycystic Ovary group, 48% had vaginal delivery,14% had assisted vaginal delivery and 37.5% had Caesarean births. Among normal group, 62% had vaginal delivery, 9% has Assisted Vaginal Delivery,28% had Caesarean births.
Conclusion: Gestational Diabetes mellitus and Polycystic Ovarian Syndrome are the emerging diseases that not only affects the quality of life of the patients but also have genetic influences that carry over to the next generations and hence appropriate diagnosis and treatment are necessary.
Indexed in Index Copernicus
