Abstract: The worldwide incidence of Ovarian Cancer in pregnancy is 0.04-0.11 per 1000, making it the second most common gynaecological malignancy in pregnant women. With an increase in the average age for child-bearing and routine use of ultrasonography during pregnancy, the grim diagnosis of ovarian malignancy during pregnancy is on the rise. The optimum management of such cases is challenging because of limitations in the diagnostic modalities and ethical concerns regarding chemo-radiotherapy and surgery. These cases require a multidisciplinary approach involving the obstetrician, medical oncologist, neonatologist and/or other specialities with the common goal of balancing the well-being of the mother against the survival of the foetus.
We report two cases of ovarian malignancy; one was an advanced case of high grade serous ovarian cancer and the other was a case of mucinous cystadenocarcinoma. While one patient had a favourable outcome with a healthy baby delivered at term, the other patient delivered a small for gestation (SGA) foetus at 32 weeks following which she had extensive chemotherapy and surgery followed by 2 episodes of recurrence.
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