Abstract: Background: The measurement of myometrial thickness by ultrasound may be helpful in the management of pregnancy with preterm premature rupture of membranes (PPROM) and threatened preterm labor. The aim of this work was to assess the value of myometrial thickness measurement as a method in prediction of latency period in women with PPROM till delivery.
Methods: This case control study was carried out on 120 pregnant women aged from 20 to 35 years old, gestational age (GA) between 28 to 36 weeks, singleton pregnancy with premature rupture of membrane.Patients were divided into two equal groups: Group A: PPROM and were subdivided into four subgroups according to GA: [Group A1: 28 to 29 week +6 days, group A2: 30-to-31-week +6 days, group A3: 32 to 33 week +6 days and group A4: 34 to 36 week] and group B: normal pregnancy as control which subdivided into four subgroups according to GA: [Group B1: 28 to 29 week +6 days, group B2: 30 to 31 week +6 days, group B3: 32 to 33 week +6 days and group B4: 34 to 36 week].
Results: Fundal myometrial thickness and anterior wall myometrial thickness were significantly lower in group A1, A2, A3 and A4 than group B1, B2, B3 and B4 (p<0.001). Anterior wall myometrial thickness and fundal myometrial thickness can significantly predict labor (p<0.001). Posterior wall myometrial thickness can’t predict labor (P =0.596, 0.400).
Conclusions: PPROM is associated with decreased thickness of anterior wall and fundal myometrial thickness. Anterior wall and fundal myometrial thickness measurement can predict labor and their thickness are increased with latency period.
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