Abstract: Background: Asymptomatic thrombocytopenia during pregnancy is a common yet often overlooked condition, characterized by a platelet count below 150,000/µL without accompanying clinical symptoms. This research aims to provide an in-depth analysis of the incidence, and clinical outcomes of asymptomatic thrombocytopenia in pregnant women. Thrombocytopenia affects 7 to 11% of all pregnancies. Asymptomatic thrombocytopenia, in contrast, often goes unnoticed unless routine blood tests are performed. This research aims to comprehensively study on asymptomatic thrombocytopenia in pregnancy, focusing on its incidence, and clinical outcomes.
Methods: We conducted a prospective observational study to identify pregnant women with asymptomatic thrombocytopenia. The study was conducted in the department of obstetrics and gynecology at R.D. Gardi Medical College during a one-year and six-month period, from June 1, 2023, to November 31, 2024. All the pregnant women who were admitted preferably after 28 weeks of gestation till term pregnancy were included.
Results: We had screened about 1572 pregnant women out of which 119 were found to be thrombocytopenia in pregnancy. The prevalence recorded in our study was 7.5% and 65%, 21%, 13% of the women were found to have mild, moderate and severe thrombocytopenia respectively. In our research, we observed a prevalence of 7.5%, with 65%, 21%, and 13% of the women presented with mild, moderate, and severe thrombocytopenia, respectively.
Conclusion: Asymptomatic thrombocytopenia in pregnancy, is usually benign and self-limiting. This research highlights that the majority of cases are attributable to gestational thrombocytopenia, which typically presents with mild platelet reduction and minimal clinical consequences. However, distinguishing this from more severe causes such as preeclampsia, eclampsia, HELLP Syndrome, dengue fever, APH needs critical care and appropriate management. Timely diagnosis and differentiation can prevent unnecessary interventions and guide safe obstetric care.
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