Background: Ovarian masses may occur in various demographics. Most masses are diagnosed late due to ambiguity of the clinical presentation. The most common symptom is pain abdomen which is nonspecific. Pelvic ultrasonography is used to aid clinical examination to come to an early diagnosis and treatment. Final diagnosis is given by histopathological examination of ovarian mass tissue which is obtained through various surgical methods. In this study the correlation of clinal, radiological and histopathological correlation is studied.
Aim: to study the clinical and histopathological correlation in patients with ovarian masses in various demographics
Methods: 40 women who had ovarian masses from July 2023 to December 2024 were chosen for the study after fulfilling the inclusion criteria. Patient’s history, examination findings, ultrasonography findings along with the histopathological report were noted for the study.
Results: In the present study majority of the patients were in the age group 21 - 30 years old (35%). Majority of the patients were married at the ages between 18-25 years (47.5%). 62.5% of the patients with ovarian masses had their first child between the ages of 18-25 years. Majority of the patients with ovarian masses are parous women. 45% of the cases with ovarian masses had two children. In the present study majority of the patients with ovarian masses were pre-menopausal (87.5%). Patients who presented with ovarian masses were more likely to be overweight constituting 27.5% of the total study group. The most common symptom the patients showed was pain abdomen (42%). It was observed that most of the patients had symptoms for less than 6 months (73%). On examination it was observed that 55% of palpable masses were cystic and 45% were solid. It was noted that majority of the patients in the study had CA-125 levels less that 35IU/ml constituting 57% of the total study group. Based on ultrasound findings it was observed that majority of the ovarian masses were <7cm, constituting 60%. 92.5% were unilateral, 70% did not have internal echoes, 62.5% were unilocular, 70 did not have septations, and 97.5% did not have ascites. The commonly done surgery was unilateral cystectomy constituting 37.5%. On histopathological examination the most common finding was luteal cyst.
Conclusion: In the current study with 40 cases of ovarian masses which match the inclusion criterion were taken into the study and analyzed. The patient history, clinical examination, tumor markers, ultrasound findings and histopathological examination findings were considered for the present study. Prevalence of ovarian masses in various demographics observed. Patients were classified according to their history, clinical findings, radiological findings and histopathological findings, correlation and comparison noted.