Introduction: Pre-eclampsia (PE) is a multisystem hypertensive disorder of pregnancy characterized by new-onset hypertension and proteinuria or evidence of end-organ dysfunction after 20 weeks of gestation in a previously normotensive woman.
Aims: The study aimed to determine the incidence of microalbuminuria in pregnant women and its correlation with preeclampsia. It also evaluated the urinary albumin-creatinine ratio (ACR) as a screening test and assessed its association with adverse fetal outcomes such as preterm delivery, IUGR, and IUFD.
Materials and Methods: A prospective cross-sectional study was conducted at the Department of Obstetrics and Gynecology, Medical College Baroda and Shri Sayaji General Hospital from 1st June 2008 to 31st May 2009. The study included pregnant women attending the antenatal outpatient department during the study period.
Results: In our study of 110 pregnant women, higher ACR levels were associated with increased severity of preeclampsia. PIH was more common in primigravida, preterm deliveries, and LSCS cases, and was linked to a higher incidence of IUGR, indicating its impact on adverse maternal and fetal outcomes.
Conclusion: In summary, the study found that higher urinary albumin-creatinine ratios were linked to increased severity of pre-eclampsia and adverse pregnancy outcomes such as preterm delivery, cesarean section, and IUGR. Hypertension was more frequent in both first-time and multiparous mothers. Regular monitoring of ACR in mid-pregnancy proved to be an effective screening tool for early detection and management of pre-eclampsia, improving maternal and fetal outcomes.
International Journal of Clinical Obstetrics and Gynaecology
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