Background: Accurate preoperative assessment of peritoneal carcinomatosis (PC) is crucial in ovarian cancer for determining the feasibility of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Various imaging modalities, including PET-CT, CT, and MRI, are commonly used to evaluate the Peritoneal Carcinomatosis Index (PCI), but their comparative efficacy remains understudied.
Objective: To compare the accuracy of PET-CT, CT, and MRI in assessing PCI in ovarian cancer patients and determine their clinical relevance in surgical decision-making.
Methods: A cohort of 33 ovarian cancer patients was analyzed, with each patient undergoing PET-CT, CECT, and MRI preoperatively. The surgical PCI scores were used as the gold standard for comparison. Sensitivity, specificity, and correlation of imaging modalities with surgical findings were evaluated.
Results: PET-CT demonstrated the highest sensitivity and specificity for detecting peritoneal metastases, accurately predicting PCI in 10 out of 14 cases. CT and MRI showed lower accuracies, with CT predicting PCI correctly in 5 out of 13 cases and MRI in 3 out of 6 cases. PET-CT had the strongest correlation with surgical PCI scores, highlighting its superiority in preoperative staging.
Conclusion: PET-CT is the most reliable imaging modality for evaluating PCI in ovarian cancer, offering significant clinical benefits in surgical planning. Its superior sensitivity and specificity make it an essential tool in assessing peritoneal metastasis and guiding treatment decisions.
International Journal of Clinical Obstetrics and Gynaecology
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