International Journal of Clinical Obstetrics and Gynaecology

Introduction: HELLP syndrome is a severe complication of pre-eclampsia. It represents a major obstetric emergency that can be life-threatening for both mother and fetus.

Objective; study its epidemiological, clinical, therapeutic and prognostic aspects of the HELLP syndrome

Patients and Methods: This was a descriptive cross-sectional study covering the period from January,1^st 2020 to August, 31^st 2024. It concerned the files of patients hospitalized in the gynecology and obstetrics department of N’Djamena Mother and child university hospital. Pregnant patients (term ? 20 weeks of gestation) or in the postpartum period with a complete assessment meeting the criteria for the definition of HELLP syndrome.

Data was collected using a survey form containing sociodemographic, clinical, paraclinical, therapeutic and prognostic variables. The analysis was performed using Word and Excel software.

Results: We collected 47 cases amo,g 21,026 patients admitted in the department, giving a frequency of 0.22%. The average age was 24±6.91 years, and the most represented age group was 20-24 years (34.04%). Primigravidas accounted for 38.30%. The diagnosis was often made in antepartum representing 78.72%) The most commonly reported symptoms were headaches and convulsions, occurring in 68.09% and 57.45% of cases, respectively. Caesarean sections accounted for 64.86% of deliveries. Maternal deaths and stillbirths accounted respectively for 27.66% and 40.54%.