International Journal of Clinical Obstetrics and Gynaecology

A clinical predictive test to be useful for PIH it should be simple, innocuous, impose minimal discomfort on the women, technology should be widely available, rapid, inexpensive, noninvasive, easy to perform in early pregnancy. Results of the test must be valid reliable and reproducible, very high likelihood for a positive test result and low likelihood ratio for a negative test result Biological, biochemical and biophysical markers implicated in pathophysiology of preeclampsia have been proposed to predict its development. All the pregnant women with ? 20 weeks of gestation who fulfilled the selection criteria registered in the Department of Obstetrics and Gynaecology, enrolled in this study. A total of 151 women registered in the Department of Obstetrics and Gynaecology, during the study period were studied. All the women fulfilling the selection criteria were explained about the nature of the study and a written informed consent was obtained before enrollment. In the present study serum LDH levels ranged between 245 to as high as 5692 IU/L. The mean LDH Levels were 742.4±545.20 IU/L and median levels were 677 IU/L. These findings suggest that, the serum LDH levels were high in the population studied which is likely to be the fact that, there were 101 preeclamptic women as against 50 women with normal pregnancy. Further, more than one third (41.72%) of the women had normal LDH levels (< 600 IU/L), 31.13% of the women had raised LDH levels (between 600 to 800 IU/L) and 27.15% of the women had LDH Levels profoundly raised LDH levels (> 800 IU/L).