International Journal of Clinical Obstetrics and Gynaecology

Pre-eclampsia is a multisystem disorder that complicates 3%-8% of pregnancies in Western countries and constitutes a major source of morbidity and mortality worldwide. Overall, 10%-15% of maternal deaths are directly associated with pre-eclampsia and eclampsia. Some epidemiological findings support the hypothesis of a genetic and immunological etiology. After obtaining written informed consent, demographic data such as age, detailed history (including obstetric history, family history and other comorbid conditions) was obtained through an interview. Also presenting complaints were noted. Further these women were subjected to complete examination (general and systemic examination). In the present study maternal mortality was noted in eight women and the causes of mortality in two women each (25%) were abruption, DIC and intracranial bleed. In this study maternal mortality was noted in 5.3% of the women and all women had LDH levels of > 800 IU/L (p<0.001). In the present study neonatal mortality noted only in mothers with LDH levels of >800 IU/L (32.26%) (p<0.001).